Customer Support: 131 242

  • There are no items in your cart
We noticed you’re not on the correct regional site. Switch to our AMERICAS site for the best experience.
Dismiss alert

BS ISO 16702:2007

Current
Current

The latest, up-to-date edition.

Workplace air quality. Determination of total organic isocyanate groups in air using 1-(2-methoxyphenyl) piperazine and liquid chromatography
Available format(s)

Hardcopy , PDF

Language(s)

English

Published date

31-03-2008

Foreword
Introduction
1 Scope
2 Normative references
3 Terms and definitions
4 Principle
5 Reagents and materials
6 Apparatus
7 Sampling
   7.1 Calibration of pump
   7.2 General
   7.3 Preparation of sampling equipment (general)
   7.4 Preparation of sampling equipment (filters)
   7.5 Preparation of sampling equipment (impingers)
   7.6 Collection of filter samples (vapour phase samples)
   7.7 Collection of impinger backed by filter samples
        (isocyanate aerosols)
   7.8 Measurements to be made at the end of the sampling
        period
   7.9 Sample logging and field desorption of samples
   7.10 Transportation
   7.11 Field Blanks
8 Procedure
   8.1 Safety precautions
   8.2 Cleaning of glassware
   8.3 Prereaction of impinger samples before HPLC analysis
   8.4 Prereaction of filter samples before HPLC analysis
   8.5 HPLC conditions
   8.6 Determination of airborne isocyanate for monomeric
        isocyanates (UV detection)
   8.7 Identification of polymeric isocyanates: EC/UV ratio
        approach
   8.8 Confirmation of identification for polymeric isocyanates
        (prepolymers)
   8.9 Quantification of airborne isocyanate for polymeric
        isocyanates (EC detection)
   8.10 Sampling efficiency
9 Calculations
10 Interferences
11 Uncertainty of measurement
   11.1 Introduction
   11.2 Assessment of performance characteristics of the method
        - Sampling considerations (detailed ISO/IEC Guide 98:1995
        approach)
   11.3 Assessment of performance characteristics of the method -
        - Other considerations - (detailed ISO/IEC Guide 98:1995
        approach)
   11.4 Mass of compound in field sample blank
   11.5 Between-laboratory uncertainty contributions
   11.6 Combined uncertainty
   11.7 Expanded uncertainty
12 Stability
13 Test report
14 Quality control
Annex A (informative) - Determination of sampling efficiency
Annex B (informative) - Data used for uncertainty estimates
Annex C (informative) - Combined uncertainties for isocyanate
        formulations
Annex D (informative) - Sample chromatograms
Bibliography

Provides general guidance for the sampling and analysis of airborne organic isocyanate (NCO) compounds in workplace air.

This International Standard gives general guidance for the sampling and analysis of airborne organic isocyanate (NCO) compounds in workplace air.

This International Standard is appropriate for a wide range of organic compounds containing isocyanate functional groups, including isocyanate monomers and prepolymers. Examples of aromatic monomers include toluene diisocyanate (TDI) (both 2,4- and 2,6-diisocyanatotoluene), naphthyl diisocyanate (NDI) (1,5-diisocyanatonaphthalene) and methylenebis(4-phenylisocyanate) [MDI, systematically named as di-(4-isocyanatophenyl)methane]. Examples of aliphatic monomers include isophorone diisocyanate (IPDI, systematically named as 1-isocyanato-3-isocyanatomethyl-3,5,5-trimethylcyclohexane), methylenebis(cyclohexylisocyanate) (hydrogenated MDI, HMDI) and 1,6-diisocyanatohexane (HDI) (also known as 1,6-hexamethylenediisocyanate). Monomers containing a single isocyanate moiety (e.g. methyl isocyanate, ethyl isocyanate, phenyl isocyanate, hexyl isocyanate) are produced during thermal degradation of polyurethanes, i.e. flame bonding and laser cutting. Isocyanate polymers, also called polyisocyanates, homopolymers, oligomers or prepolymers, are derived from the diisocyanate monomers by self-condensation or reaction with polyols. Polymeric diisocyanates are widely used in the polyurethanes, paints and coatings, and adhesives industries.

This International Standard is appropriate for measuring any product containing free isocyanate groups. It was developed primarily for the commonly used MDI, HDI, and TDI, and their oligomers and polymers[1]. It has also been used for IPDI, HMDI, and NDI, and their oligomers and polymers. The exposure limit for isocyanates in the UK requires measurement of total isocyanate groups, i.e. monomeric diisocyanates, oligomeric, prepolymeric and polymeric diisocyanates and monoisocyanates. Because there are a wide range of isocyanate structures and molecular masses, the chromatographic conditions used will need to be varied according to the isocyanate formulation being determined. If both isocyanates and amines are believed to be present, and both need to be determined, a standard which enables the simultaneous determination of both amines and isocyanates may be more appropriate[2]. This method has also been modified to allow determination of mono-isocyanates produced during thermal degradation[3], the use of mass spectrometric detection[4] and other sampling equipment, e.g. 37mm filters and other filter cassettes, but these modifications are not covered in this International Standard. If a modified version of this method is being used, it is the responsibility of the user to demonstrate that the modifications are valid.

The method is used to determine time-weighted average concentrations of organic isocyanates in workplace atmospheres, and is suitable for sampling over periods in the range 0,5min to 8h. The method is designed for personal monitoring, but can also be used for fixed location monitoring by suitable modification.

NOTE The objective of air monitoring is usually to determine worker exposure and, therefore, the procedures described in this method are for personal sampling in the breathing zone. The method can be used for background or fixed location sampling. However, it should be recognised that, due to aerodynamic effects, samplers designed for personal sampling do not necessarily exhibit the same collection characteristics when used for other purposes.

The method is suitable for the measurement of airborne organic isocyanates in the concentration range from approximately 0,1µg/m3 to 140µg/m3 for a 15l sample volume. The qualitative and quantitative detection limits for isocyanate, defined as three times and 10 times the standard deviation of six blank determinations, have been found to be typically between 0,001µg and 0,004µg of isocyanate per sample, respectively (EC detection). For a 15l air sample, these values correspond to qualitative and quantitative detection limits of 0,07µg/m3 and 0,3µg/m3, respectively.

Committee
EH/2/2
DevelopmentNote
Supersedes 99/563364 DC (08/2002) Supersedes 05/30143410 DC. (04/2008)
DocumentType
Standard
Pages
44
PublisherName
British Standards Institution
Status
Current
Supersedes

Standards Relationship
ISO 16702:2007 Identical

ISO/IEC Guide 98:1993 Guide to the expression of uncertainty in measurement (GUM)
EN 482:2012+A1:2015 Workplace exposure - General requirements for the performance of procedures for the measurement of chemical agents
ISO 17734-2:2013 Determination of organonitrogen compounds in air using liquid chromatography and mass spectrometry — Part 2: Amines and aminoisocyanates using dibutylamine and ethyl chloroformate derivatives
ISO 16200-1:2001 Workplace air quality — Sampling and analysis of volatile organic compounds by solvent desorption/gas chromatography — Part 1: Pumped sampling method
EN 13205:2001 Workplace atmospheres - Assessment of performance of instruments for measurement of airborne particle concentrations
ISO 5725-2:1994 Accuracy (trueness and precision) of measurement methods and results Part 2: Basic method for the determination of repeatability and reproducibility of a standard measurement method
EN 1232:1997 Workplace atmospheres - Pumps for personal sampling of chemical agents - Requirements and test methods

View more information
$478.43
Including GST where applicable

Access your standards online with a subscription

Features

  • Simple online access to standards, technical information and regulations.

  • Critical updates of standards and customisable alerts and notifications.

  • Multi-user online standards collection: secure, flexible and cost effective.

Need help?
Call us on 131 242, then click here to start a Screen Sharing session
so we can help right away! Learn more