Name: ASTM E 1163 : 2010 : R2019
Brand: ASTM
Price: 45.92 GBP

Standard Test Method for Estimating Acute Oral Toxicity in Rats

Available format(s)

Hardcopy , PDF

Language(s)

English

Published date

01-02-2019

Publisher

American Society for Testing and Materials

This test method determines the lethality (LD50 value, slope and 95 % confidence interval (CI)) and signs of acute toxicity from a material using a limited number of rats.

1.1This test method determines the lethality (LD50 value, slope and 95 % confidence interval (CI)) and signs of acute toxicity from a material using a limited number of rats. The technique used in this test method is referred to as the “Stagewise, Adaptive Dose Method.”2 This test method is an alternative to the classical LD50 test and is applicable to both liquids and solids.

1.2This test method is not recommended for test materials which typically produce deaths beyond two days postdosing.

1.3This standard does not purport to address all of the safety concerns, if any, associated with its use. It is the responsibility of the user of this standard to establish appropriate safety, health, and environmental practices and determine the applicability of regulatory limitations prior to use.

1.4This international standard was developed in accordance with internationally recognized principles on standardization established in the Decision on Principles for the Development of International Standards, Guides and Recommendations issued by the World Trade Organization Technical Barriers to Trade (TBT) Committee.

Committee	E 50
DocumentType	Test Method
Pages	3
PublisherName	American Society for Testing and Materials
Status	Current
Supersedes	ASTM E 1163 : 2010 : R2016

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ASTM E 1163 : 2010 : R2019

Standard Test Method for Estimating Acute Oral Toxicity in Rats

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