Water quality. Evaluation of genotoxicity by measurement of the induction of micronuclei Mixed population method using the cell line V79

Available format(s)

Hardcopy , PDF

Language(s)

English

Published date

31-07-2009

Publisher

British Standards Institution

Foreword
1 Scope
2 Normative references
3 Terms and definitions
4 Principle
5 Interferences
6 Reagents and media
7 Apparatus
8 Test facility criteria
9 Procedure
10 Evaluation and assessment
11 Precision
12 Test report
Annex A (informative) - Bromodeoxyuridine (BrdU) method
Annex B (informative) - Evaluation schemes
Annex C (normative) - S9 fraction
Annex D (informative) - Precision data
Bibliography

Describes a method for the determination of genotoxicity of water and waste water using a mammalian in vitro test which detects damage, induced by water-soluble substances, to the chromosomes or the mitotic apparatus of V79 cells from the Chinese hamster.

Committee	EH/3/5
DevelopmentNote	Also numbered as BS 6068-5.45(2006). Supersedes 05/30106320 DC. Renumbers and supersedes BS ISO 21427-2. 2009 version incorporates corrigendum to BS ISO 21427-2. (07/2009)
DocumentType	Standard
Pages	28
PublisherName	British Standards Institution
Status	Current
Supersedes	05/30106320 DC : DRAFT APR 2005 BS ISO 21427-2 : 2006

Standards	Relationship
EN ISO 21427-2:2009/AC:2009	Identical
ISO 21427-2:2006	Identical
ISO 21427-2:2006/Cor 1:2009	Identical
EN ISO 21427-2:2009	Identical

ISO 13829:2000	Water quality Determination of the genotoxicity of water and waste water using the umu-test
ISO 5667-10:1992	Water quality Sampling Part 10: Guidance on sampling of waste waters
ISO 5667-2:1991	Water quality Sampling Part 2: Guidance on sampling techniques
ISO 5667-14:2014	Water quality Sampling Part 14: Guidance on quality assurance and quality control of environmental water sampling and handling
ISO 5667-3:2012	Water quality Sampling Part 3: Preservation and handling of water samples
ISO 5667-1:2006	Water quality Sampling Part 1: Guidance on the design of sampling programmes and sampling techniques
ISO 16240:2005	Water quality Determination of the genotoxicity of water and waste water Salmonella/microsome test (Ames test)
ISO/TS 20281:2006	Water quality — Guidance on statistical interpretation of ecotoxicity data
ISO 5667-16:2017	Water quality — Sampling — Part 16: Guidance on biotesting of samples

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BS EN ISO 21427-2:2009

Water quality. Evaluation of genotoxicity by measurement of the induction of micronuclei Mixed population method using the cell line V79

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Abstract

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