Workplace atmospheres — Determination of toluene diisocyanate vapours using 1-(2-pyridyl)piperazine-coated glass fibre filters and analysis by high performance liquid chromatography with ultraviolet and fluorescence detectors

Available format(s)

Hardcopy , PDF , PDF 3 Users , PDF 5 Users , PDF 9 Users

Language(s)

English

Published date

06-12-2012

Publisher

International Organization for Standardization

This International Standard gives general guidance for the sampling and analysis of airborne toluene diisocyanate (TDI) in workplace atmospheres. The procedure specified in this International Standard is especially suitable for short (15 min) and long-term (4 h) sampling and analysis of 2,4- and 2,6-TDI vapours.

The upper limit for this method is approximately 85 µg of TDI per sample. This is a conservative upper limit based on the requirement of maintaining a sufficient amount of reagent on the coated glass fibre filter while permitting a 4 h sample to be collected at 1 l/min from an atmosphere containing 50 nl/l of TDI.

The quantitation limits for this method are 0,039 µg for 2,4-TDI and 0,034 μg for 2,6-TDI using a fluorescence detector. These limits, for a 15-min sample collected at 1 l/min, are equivalent to 0,36 nl/l for 2,4-TDI, and 0,32 nl/l for 2,6-TDI. For a 4 h sample collected at 1 l/min, the limits are equivalent to 0,022 nl/l for 2,4-TDI and 0,020 nl/l for 2,6-TDI.

The commercial availability of the specified reagents, the use of common analytical instrumentation, and the current widespread use of the method make this standard method ideally suited for the determination of TDI in workplace environments.

Committee	ISO/TC 146/SC 2
DevelopmentNote	Supersedes ISO/DIS 14382. (12/2012)
DocumentType	Standard
Pages	20
PublisherName	International Organization for Standardization
Status	Current

Standards	Relationship
UNI ISO 14382: 2022	Identical
BS ISO 14382:2012	Identical
GOST R ISO 14382 : 2015	Identical

ISO 1042:1998	Laboratory glassware One-mark volumetric flasks
EN 482:2012+A1:2015	Workplace exposure - General requirements for the performance of procedures for the measurement of chemical agents
ISO 17735:2009	Workplace atmospheres Determination of total isocyanate groups in air using 1-(9-anthracenylmethyl)piperazine (MAP) reagent and liquid chromatography
ISO 17736:2010	Workplace air quality Determination of isocyanate in air using a double-filter sampling device and analysis by high pressure liquid chromatography
ISO 16200-1:2001	Workplace air quality — Sampling and analysis of volatile organic compounds by solvent desorption/gas chromatography — Part 1: Pumped sampling method
ISO 5725-2:1994	Accuracy (trueness and precision) of measurement methods and results Part 2: Basic method for the determination of repeatability and reproducibility of a standard measurement method
ENV 13005 : DRAFT 1999	GUIDE TO THE EXPRESSION OF UNCERTAINTY IN MEASUREMENT
EN 1232:1997	Workplace atmospheres - Pumps for personal sampling of chemical agents - Requirements and test methods
ISO/IEC Guide 98-3:2008	Uncertainty of measurement — Part 3: Guide to the expression of uncertainty in measurement (GUM:1995)