ISO 23970:2021
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The latest, up-to-date edition.
Milk, milk products and infant formula Determination of melamine and cyanuric acid by liquid chromatography and tandem mass spectrometry (LC-MS/MS)
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French, English
16-09-2021
This document specifies a method for the determination of melamine and cyanuric acid with liquid chromatography in combination with tandem mass spectrometry (LC-MS/MS). The method has been validated in an interlaboratory study via the analysis of spiked samples of milk-based infant formula, soy-based infant formula, milk powder, whole milk, soy drink and milk chocolate ranging from 0,71mg/kg to 1,43mg/kg for melamine and 0,57mg/kg to 1,45mg/kg for cyanuric acid. The limits of quantification (LOQ) for melamine and cyanuric acid in food are 0,05mg/kg and 0,25mg/kg, respectively. The upper limit of the working range is up to 10mg/kg for melamine and up to 25mg/kg for cyanuric acid.
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