BS ISO 21676 - WATER QUALITY - DETERMINATION OF SELECTED ACTIVE PHARMACEUTICAL INGREDIENTS, TRANSFORMATION PRODUCTS AND OTHER ORGANIC SUBSTANCES IN WATER AND TREATED WASTE WATER - METHOD USING HIGH PERFORMANCE LIQUID CHROMATOGRAPHY AND MASS SPECTROMETRIC DETECTION (HPLC-MS/MS OR - HRMS) AFTER DIRECT INJECTION

Available format(s)

Hardcopy , PDF

Language(s)

English

Publisher

British Standards Institution

Foreword
Introduction
1 Scope
2 Normative references
3 Terms and definitions
4 Principle
5 Interferences
6 Reagents
7 Apparatus
8 Sampling
9 Procedure
10 Calibration
11 Calculation of recovery
12 Evaluation
13 Expression of results
14 Test report
Annex A (informative) - Performance data
Annex B (informative) - Examples of recovery
Annex C (informative) - Examples of HPLC columns and chromatograms
Annex D (informative) - Examples of detection
Annex E (informative) - Examples of extension of the method
Bibliography

BS ISO 21676.

Committee	EH/3/2
DocumentType	Draft
Pages	42
PublisherName	British Standards Institution
Status	NA

ISO 4796-2:2000	Laboratory glassware — Bottles — Part 2: Conical neck bottles
ISO 1042:1998	Laboratory glassware One-mark volumetric flasks
ISO 11352:2012	Water quality — Estimation of measurement uncertainty based on validation and quality control data
ISO 5667-4:2016	Water quality Sampling Part 4: Guidance on sampling from lakes, natural and man-made
ISO 5667-6:2014	Water quality Sampling Part 6: Guidance on sampling of rivers and streams
ISO 5725-2:1994	Accuracy (trueness and precision) of measurement methods and results Part 2: Basic method for the determination of repeatability and reproducibility of a standard measurement method
ISO 3696:1987	Water for analytical laboratory use — Specification and test methods
ISO 5667-5:2006	Water quality Sampling Part 5: Guidance on sampling of drinking water from treatment works and piped distribution systems
ISO 8466-1:1990	Water quality Calibration and evaluation of analytical methods and estimation of performance characteristics Part 1: Statistical evaluation of the linear calibration function
ISO 5667-11:2009	Water quality Sampling Part 11: Guidance on sampling of groundwaters