This document specifies a method for the quantitative determination of calcium (Ca), copper (Cu), iron (Fe), magnesium (Mg), manganese (Mn), phosphorus (P), potassium (K), sodium (Na), zinc (Zn), chromium (Cr), molybdenum (Mo) and selenium (Se) using inductively coupled plasma and mass spectrometry (ICP-MS). The method is applicable for the determination of all 12 elements in infant formula and adult nutritional products. The method is also applicable for milk, milk powder, whey powder, butter and cheese excluding the determination of Cr, because all Cr results were below the quantification limit and reproducibility could not be determined in these matrices[1]. The present method is an extension of ISO20649|IDF235 (AOAC2011.19[2]) which was validated only for Cr, Mo and Se in infant formula and adult nutritional products. The ranges given in Table1 are in scope (see also TableA.1). Table1Analytical ranges Ca Cu Fe Mg Mn P K Na Zn Cr Se Mo Lower analytical rangea, in mg/100g 3 0,002 0,04 0,7 0,002 3 3 2 0,07 0,002 0,0006 0,0002 Upper analytical rangea, in mg/100g 1280 1,2 20 110 1,0 800 2000 850 18 0,16 0,05 0,10 a Concentrations apply to — milk and ??ready-to-feed?? liquid as-is, using a typical sample size of 1g per final analytical solution volume of 50ml, and — reconstituted milk powder, reconstituted infant formula powder and reconstituted adult nutritional powder (25g into 200g of water), using a typical sample size of 1,8g of the reconstituted slurry per final analytical solution volume of 50ml. Ranges for non-reconstituted dairy ingredients (butter, cheese, whey powder, whey protein concentrate) are adjusted proportionally upward from these values based upon the sample size used for the ingredient. For example, if 0,3g of cheese is digested the ranges will be 1g/ 0,3g=3,3×higher.