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BS ISO 10130:2009

BS ISO 10130:2009

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Current

The latest, up-to-date edition.

Cosmetics. Analytical methods. Nitrosamines. Detection and determination of N-nitrosodiethanolamine (NDELA) in cosmetics by HPLC, post-column photolysis and derivatization

Available format(s)

Hardcopy , PDF

Language(s)

English

Published date

06-30-2010

Publisher

British Standards Institution

Foreword
Introduction
1 Scope
2 Principle
3 Reagents
4 Apparatus
5 Sample preparation and storage
6 Procedure
7 Calculation of results
8 Test report
Annex A (informative) - Examples of calibration curves
        and typical chromatograms
Annex B (normative) - Photolysis and reaction of nitrite
        with Griess reagent to form the azo dye
Annex C (normative) - Configuration of the post-column
        reactor system
Bibliography

Specifies a method for the detection and quantification of N-nitrosodiethanolamine (NDELA) in cosmetics and raw materials used in cosmetics by high performance liquid chromatography (HPLC) coupled with post-column photolysis and derivatization.

This International Standard describes a method for the detection and quantification of N-nitrosodiethanolamine (NDELA) in cosmetics and raw materials used in cosmetics by high performance liquid chromatography (HPLC) coupled with post-column photolysis and derivatization.

This method is not applicable to the detection and/or quantification of nitrosamines other than NDELA, nor to the detection and/or quantification of NDELA in products other than cosmetics or raw materials used in cosmetics.

If a product has the possibility of either NDELA contamination from the ingredients or NDELA formation by the composition of ingredients, the method will be applied for the testing of cosmetic products and is an alternative to ISO15819.

This method is not applicable to matrices containing oxidation dyes.

Committee
CW/217
DevelopmentNote
Supersedes 08/30174283 DC. (07/2010)
DocumentType
Standard
Pages
24
PublisherName
British Standards Institution
Status
Current
Supersedes

Standards Relationship
ISO 10130:2009 Identical

ISO 15819:2014 Cosmetics Analytical methods Nitrosamines: Detection and determination of N-nitrosodiethanolamine (NDELA) in cosmetics by HPLC-MS-MS

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PDF - English
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