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BS ISO 15819:2014

BS ISO 15819:2014

Current

Current

The latest, up-to-date edition.

Cosmetics. Analytical methods. Nitrosamines: Detection and determination of N-nitrosodiethanolamine (NDELA) in cosmetics by HPLC-MS-MS

Available format(s)

Hardcopy , PDF

Language(s)

English

Published date

11-30-2014

Publisher

British Standards Institution

Foreword
Introduction
1 Scope
2 Normative references
3 Principle
4 Reagents
5 Apparatus
6 Sample preparation and conservation
7 Procedure
8 Calculation of results
9 Test report
Annex A (informative) - Examples of a calibration
        curve and of chromatograms
Bibliography

Provides a method for the detection and quantification of N-nitrosodiethanolamine (NDELA) in cosmetics and raw materials used in cosmetics.

This International Standard describes a method for the detection and quantification of N-nitrosodiethanolamine (NDELA) in cosmetics and raw materials used in cosmetics.

This method is not applicable to the detection and/or quantification of nitrosamines other than NDELA nor to the detection and/or quantification of NDELA in products other than cosmetics or raw materials used in cosmetics.

If a product has a possibility of either NDELA contamination from ingredients or NDELA formation by the composition of ingredients, the method is intended to be applied for quantitative determination of NDELA. Accordingly, the method does not apply to routine testing of cosmetic products. Because of the large variety of cosmetic products within this field of application, this method might need to be adapted for certain matrices (refer to ISO12787).

Therefore, International Standards dedicated to alternative methods for testing nitrosamines in cosmetic products are being developed separately. Other methods can be employed provided that they are verified as to their detection of NDELA and validated in terms of recovery and quantification of the analyte.

Committee
CW/217
DevelopmentNote
Supersedes 13/30278599 DC. (11/2014)
DocumentType
Standard
Pages
22
PublisherName
British Standards Institution
Status
Current
Supersedes

Standards Relationship
ISO 15819:2014 Identical

ISO 3696:1987 Water for analytical laboratory use — Specification and test methods
ISO 12787:2011 Cosmetics Analytical methods Validation criteria for analytical results using chromatographic techniques

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PDF - English
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